Most users only use a single signature when sending emails but there are few who work at two or more places and need to use different signatures. Users can create multiple signatures in Outlook 2010 and quickly add them on different emails in just 2 clicks. For example, a person using Outlook 2010 on a laptop will use a different signature at home than the one he uses while at work.
Launch Outlook 2010, go to File menu and click Options.
You will reach Outlook Options dialog, select Mail from left sidebar, and from main window click Signatures.
It will bring up Signature and Stationary dialog, click New to start
creating new signature.
Enter an appropriate name for signature and click OK.
Now start editing signature content from Edit signature pane and click Save to save the new signature
Click New to create another signature, give it a name and save it. From Edit signature pane click image button.
You will reach Insert Picture dialog, now select an image for signature
and click Insert
Image is successfully inserted into Edit Signature pane, click Save to
save the newly created signature and click OK.
You will see default signature in new email compose window for adding a
different signature from Message tab under Signature options click the
Upon clicking, it will immediately change signature to selected signature.
Now you’re all set!